Dealing with chronic pain is difficult for doctors and patients alike. For doctors, when dealing with conditions like fibromyalgia, CRPS, lipedema, and other chronic pain disorders, most treatment plans include the use of opioid painkillers. For patients, the risk of developing an unhealthy dependency on these drugs—amongst other concerns—is scary. But what if these opiate painkillers don’t even work? What are doctors supposed to do then?