The history of ketamine goes back to 1962, when it was first synthesized by American scientist, Calvin Stevens, at the Parke Davis Laboratories. The drug was known as a fast acting anesthetic and, eventually, a recreational hallucinogen. However, in the late 1990s, its antidepressive benefits were discovered. Research performed over the last two decades suggests that ketamine infusions could rapidly and effectively ease symptoms of depression and anxiety in up to 70% of patients, a discovery which marked the beginning of ketamine clinics popping up all over the country.
The mind-altering effects of psychedelic drugs may do more than just change a person’s state of consciousness. In a new study recently published in Cell Reports, researchers at the University of California, David found that substances such as LSD, DMT and MDMA actually increased the number of neural connections between brain cells. These findings could ultimately be used to repair the damaged neural connections oftentimes observed in those suffering from depression, anxiety, PTSD, and other psychiatric disorders.