Our Denver, Boulder and Fort Collins area ketamine clinics have been treating patients for several years now, a time period over which we’ve been able to watch the progression of this drug as it evolves. We’ve always known, without a doubt, that ketamine is highly effective for the treatment of such psychiatric disorders as depression, anxiety, bipolar disorder, and PTSD. However, the exact mechanism that makes ketamine such an effective antidepressant has been something of a mystery to researchers and clinicians alike.
In the 1980s, a Russian research team unveiled data indicating that ketamine may be useful in the treatment of drug and alcohol dependency. In the study, 66% of patients receiving ketamine treatments maintained abstinence for an entire year, compared to 24% who received only psychological counseling.
In August 2016, Janssen Research & Development—a Janssen Pharmaceutical Company of Johnson & Johnson—announced that an isomer of ketamine, called esketamine, had received Breakthrough Therapy Designation by the Food & Drug Administration (FDA). Similarly to ketamine, esketamine has shown huge promise as a depression treatment, especially for those experiencing suicidal ideation, or who have resisted other treatment methodologies.
Ketamine has been around since the 60s. A popular battlefield anesthetic used liberally in the Vietnam war, ketamine has experienced something of a renaissance in recent years, emerging as a powerful treatment for depression, anxiety, psychiatric disorders, and various chronic pain conditions. It's renaissance in the realm of pain management is controversial, though—according to the National Pain Report and clinicians around the country—it should not be overlooked.
Researchers first discovered the antidepressant effects of ketamine back in 2000, and have since come to recognize the drug’s ability to improve depressive symptoms—even in patients who had not responded to other methods of treatment—in a matter of hours. Private ketamine clinics, like ours, began to open their doors around 2013, bringing hope to many people who had none.
Ketamine has the potential to treat even the most severe cases of depression within a matter of hours. It has changed the lives of thousands of Americans. It has brought hope to those who have had none. And yet researchers still don’t know exactly how this drug works, the antidepressive mechanism still largely a mystery.
The holiday season is here, bringing along with it dozens of parties, days upon days of shopping, countless hours of gift wrapping, decorating, cooking, baking, entertaining…and, for millions of Americans, stress and depression. From dealing with unwelcome guests and overexcited children, to diet and exercise woes, the demands of the holiday season can be dizzying, to say the least.
It’s that time of the year. The time when friendly fall weather fades into frigid winter temperatures, cuing scarves and puffy coats, hot cocoa and cozy fires. And bringing with it millions of cases of seasonal affective disorder.
At Vitalitas Denver, we use ketamine to treat patients suffering from a wide range of chronic pain conditions. From CRPS and fibromyalgia to Lyme disease and more, ketamine is absolutely one of the most effective non-opioid pain management options available to those suffering from chronic pain. But there is another condition that we’ve been able to treat remarkably successfully through the administration of ketamine infusions: migraine headaches.
When it comes to the relationship between chronic pain and depression, it’s very much a chicken-or-the-egg type of debate. The physical manifestations of depression—while hard to explain—can be quite painful: back pain, migraine headaches, etc. The mental manifestations of chronic pain can be equally troubling: stress, difficulty sleeping, low self-esteem, etc. Chronic pain and depression oftentimes work in a vicious cycle, where pain exacerbates the symptoms of depression, which, in turn, exacerbates the feelings of physical pain. And the cycle continues…
A difficult-to-diagnose bacterial infection caused by specific types of tick bites, Lyme disease – and, more specifically, chronic Lyme disease – is a debilitating condition that can leave patients with a worse quality of life than those suffering from such disorders as congestive heart failure, diabetes, multiple sclerosis and arthritis. The symptoms of Lyme are diverse: fatigue, trouble sleeping, joint and muscle pain, depression, cognitive impairment, neuropathy, and headaches are just a few of the manifestations. No matter how chronic Lyme disease presents itself, the impact is almost always devastating.
You may or may not be familiar with complex regional pain syndrome (CRPS). CRPS is a rare – and often misunderstood – chronic pain condition. Doctors and researchers don’t understand exactly how or why CRPS develops, though it generally occurs after an injury, surgery, stroke or heart attack, and results in pain that is far worse than that of the initial injury. Like most chronic pain conditions, CRPS can improve – and can even go into remission! Of course, early intervention is key to generating the most effective pain management results.
Since the beginning of the century, statistics have favored the use of ketamine for the treatment of depression. With upwards of 70% of patients responding favorably to the depression treatment, ketamine has been hailed as the most remarkable antidepressant discovery since the 1950s.
It’s estimated that 36 million people in the United States struggle with opiate addiction. More than 80% of these addictions started with a prescribed opiate painkiller. With the opioid crisis officially declared a National State of Emergency, it’s important to know what your non-narcotic pain management options are in order to prevent substance abuse and addiction issues for you or your loved ones.
“Incredibly effective.” “Truly remarkable.” These are just a few of the comments made about the results of the latest ketamine trial – the first ever randomized control trial to study the effect of ketamine on people aged 60+ suffering from treatment resistant depression.
As the opioid epidemic continues to wreak havoc across the country, researchers are working faster and harder than ever to find alternative – but equally effective – ways to treat pain. Not surprisingly, ketamine has found itself in the mix, and the results look promising.
Ketamine has made quite a few headlines as of late. Originally introduced as an emergency room and battlefield anesthetic in the 1970s, ketamine has recently been heralded by emergency physicians and chronic pain specialists for its ability to treat chronic pain, and by mental healthcare practitioners for its ability to change the lives of patients suffering from even the most severe, treatment-resistant cases of depression.
Since 2012, it seems researchers have discovered a steady stream of new applications for ketamine. Introduced as an anesthetic in the early ‘70s, it has more recently gained popularity for its highly impressive antidepressant and antipsychotic qualities. Ketamine research shows that infusions, when administered following the proper protocol under expert supervision, dramatically improve depressive symptoms in upwards of 70% of patients. Similarly extraordinary results have manifested in ketamine studies pertaining to PTSD prevention and treatment, addiction treatment, and chronic pain management.
In life, at some point or another, everyone struggles with situational anxiety. Financial strain, emotional trauma, stress at work or school, all those anxiety-inducing what ifs. And we take a deep breath, brace ourselves, and keep moving forward the best we can. But what if you don’t?
It is hard to argue against ketamine as the most promising depression treatment available today. In 70% of patients, ketamine effectively and rapidly improves depressive symptoms, even in those patients who have historically resisted other methods of treatment. Study after study shows the same thing: ketamine works, and it works significantly better than traditional antidepressants or psychotherapy.
It’s a frustrating situation, to have this miraculous drug – a drug that is capable of changing and saving lives – so readily available, and yet so inaccessible. Without FDA approval, the overwhelming majority of insurance companies will not cover the cost of ketamine infusion therapy, leaving millions of Americans to suffer in the despair of severe depression. Private label ketamine clinics are operating around the country, but average prices of $500-800 per infusion are inhibitive at best. Even at our clinic, offering the lowest-priced ketamine infusions in the country, this potentially life-changing treatment is still not an option for many people.
Ketamine has earned its clout as one of the most effective treatments for depression, bipolar disorder and PTSD currently available on the market. However, ketamine is also effective in pain management, specifically for the treatment of chronic pain conditions, such as CRPS, migraine headaches and as a fibromyalgia treatment. Pain is the #1 cause of physical disability in the world, but modern pain management options – including opiates and other medications, physical therapy, meditation, acupuncture and other complimentary and alternative techniques – tend to treat pain symptoms as they continue to occur, rather than stopping the pain from reoccurring altogether.
Accepting the fact that you or a loved one is suffering from a mental health disorder isn’t always easy, and seeking treatment in the face of shame and stigma requires immeasurable strength. Suicide rates are at their highest levels ever. Drug addiction is wreaking havoc across the nation. Mental health disorders affect one in four people, and yet, discrimination is still alive, well, and preventing those suffering from seeking help, finding hope, and recovering.
Suicide is the second leading cause of death in adolescents and young adults. We have seen the life-changing effects that ketamine infusions can have on suicidally depressed adults, and in adults who have resisted other forms of depression treatment. When it comes to teen depression, however, few studies have explored the use of ketamine infusion therapy.
Depression is a chronic physical illness, with symptoms that are mostly invisible. Because of this, understanding depression – and knowing how to help someone with depression – is a challenge to those who are not afflicted. You walk on eggshells, afraid to say the wrong thing. You keep quiet, or give advice, albeit with good intentions, that may not be ideal or realistic for your friend or loved one to follow.
Ketamine is, by far, the most effective treatment for depression available today. Effective in 70% of patients, ketamine oftentimes works where other antidepressants have failed. In addition to being used as a depression medication, ketamine has also shown promise in PTSD prevention, the treatment of alcoholism and drug addiction, and has been used to reduce chronic pain.
Postpartum depression is complex, oftentimes confusing, and always emotionally-charged. The Centers for Disease Control (CDC) estimate that 11-20% of women who give birth– about 600,000 women every year – will experience signs of postpartum depression. Only 15% of the afflicted women, however, will seek professional counseling or medical attention. This may be because admitting to being depressed after giving birth can feel shameful. It may also be because postpartum depression generally doesn’t persist for more than six months, making it difficult to treat with psychotherapy, antidepressants, or other depression treatments that aren’t immediately effective.
Nearly 35,000 people die by suicide each year. That translates to 94 people per day, making suicide the 11th leading cause of death across all age groups. Suicide is a complex issue: there is no single cause, and, oftentimes, suicidal thoughts are never voiced and suicidal signs can be subtle.
Based on the title of Time Magazine’s latest article about ketamine as a treatment for depression, one might not even think twice about giving the long-time anesthetic a chance. The article, The Dangers of Using the Club Drug Ketamine for Depression, was published shortly after the American Psychiatric Association (APA) released their long-awaited findings and recommendations about using ketamine as an antidepressant. Contrary to what the title insinuates, the findings weren’t all bad.
Though controversial and oftentimes misunderstood, ketamine infusions have been a life-changing treatment for individuals suffering from severe depression, anxiety, and PTSD. Ketamine works when more conventional depression treatments and antidepressants fail. 70% of patients who undergo ketamine infusions experience improvement in their symptoms. Many of these patients – and their doctors – are eager to share these stories, believing that their successes may bring hope to those who are still suffering. Here are a handful of these stories.