Ketamine Therapy in Littleton, CO
Explore physician-led IV ketamine therapy for selected mental health and chronic pain conditions at our Littleton clinic, serving Highlands Ranch, Centennial, Englewood, and South Denver.
Physician-Led IV Ketamine Care Serving Littleton and South Denver
At Vitalitas, we provide medically supervised IV ketamine therapy for patients who are considering another treatment approach after standard care has not provided enough relief. At our Littleton clinic at 26 West Dry Creek Circle, Suite 200, Littleton, CO 80120, treatment begins with careful screening and an individualized recommendation based on your symptoms, health history, medications, previous care, safety factors, and goals.
Our approach is built around clear expectations rather than guarantees. Ketamine may be appropriate for some patients with persistent mental health symptoms or complex chronic pain, but not everyone is a candidate. We evaluate clinical fit first, explain what treatment involves, and review your response before making recommendations about continued care.
What IV Ketamine Therapy Is
Ketamine is a long-established medication that is FDA-approved as a general anesthetic. Its use for psychiatric conditions and chronic pain is off-label, meaning ketamine has not been FDA-approved specifically to treat the mental health and pain conditions discussed on this page. The FDA provides additional context on the current use of ketamine in emerging areas of therapeutic interest.
Ketamine is an NMDA receptor antagonist that affects glutamate signaling in the brain and nervous system. Researchers have studied these effects in mood disorders and chronic pain conditions, although the evidence, treatment protocols, and expected response vary by diagnosis.
At Vitalitas, we provide intravenous ketamine in a medically supervised setting with physician oversight and clinical monitoring.
For a deeper explanation of the treatment, research, and broader clinical context, explore our ketamine therapy overview.
Conditions We Evaluate for IV Ketamine Therapy
Vitalitas provides IV ketamine therapy through mental health and chronic pain treatment pathways. A diagnosis alone does not determine candidacy, and treatment recommendations depend on your individual history and clinical needs.
For mental health care, we may consider IV ketamine for selected patients with:
Treatment-resistant depression
Post-traumatic stress disorder (PTSD)
Anxiety and panic disorders
Obsessive-compulsive disorder (OCD)
For chronic pain care, we may consider IV ketamine for selected patients with:
Complex regional pain syndrome (CRPS/RSD)
Neuropathic pain and neuropathy
Chronic migraine and refractory headaches
Other complex or persistent chronic pain when clinically appropriate
Ketamine use for these psychiatric and chronic pain conditions is off-label.
Learn more about our mental health ketamine care and ketamine therapy for chronic pain.
How We Decide Whether Ketamine Therapy May Fit Your Care
Ketamine treatment at Vitalitas starts with a clinical evaluation, not an automatic treatment recommendation.
We consider factors including:
Your current symptoms and how they affect daily life
Mental health and medical history
Current medications
Previous treatments and response
Relevant safety and risk factors
Clinical stability
Treatment goals and expectations
Whether ketamine can be provided safely in an outpatient setting
If ketamine therapy appears appropriate, we create an individualized treatment plan. When useful, we may also coordinate with your psychiatrist, therapist, primary care clinician, pain specialist, or another provider involved in your ongoing care.
If treatment does not appear to be an appropriate fit, we believe explaining that clearly is part of responsible care.
What to Expect From IV Ketamine Treatment in Littleton
If treatment moves forward, IV ketamine is administered in a private room with physician oversight and clinical monitoring.
During treatment, we monitor:
Heart rate
Heart rhythm
Blood pressure
Oxygen level
How you are feeling during the infusion
Mental health infusions at Vitalitas are typically about 40 minutes. A common starting mental health treatment course is six infusions over approximately three to four weeks, followed by a review of your response before maintenance treatment is considered. Ongoing recommendations are individualized.
Chronic pain infusions are longer and more individualized than mental health infusions. Treatment length and frequency depend on your pain condition, clinical plan, response, tolerance, and safety needs.
After an infusion, you will need transportation home. For the remainder of the treatment day, you should avoid driving, operating heavy machinery, alcohol, intense work, and major decisions.
Follow-up is part of the treatment process. We review your response, how you are tolerating treatment, and whether continued care makes clinical sense.
Physician-Led Ketamine Treatment at Our Littleton Clinic
Vitalitas is a physician-led practice with an anesthesiology foundation. A physician anesthesiologist is present during every infusion, and treatment decisions are made within the context of your broader medical and mental health history.
Our Littleton ketamine care includes:
Careful medical and medication review
Individualized candidacy decisions
Physician involvement throughout treatment
Real-time clinical monitoring
Attention to comfort and treatment response
Follow-up and reassessment
Coordination with outside clinicians when appropriate
Ketamine can cause short-term physical and perceptual effects, which is one reason medical screening and monitoring are important. We do not assume that everyone who is interested in ketamine should receive treatment.
Ketamine Therapy Cost and Payment in Littleton
Treatment plans are individualized, but current Vitalitas pricing includes:
Clinical intake: $200 one-time intake when clinically indicated
Mental health infusions: $400 per infusion
Pain management infusions: $1,000 to $1,375 per infusion
Most insurance plans do not cover IV ketamine therapy, and Vitalitas does not bill insurance directly. We can provide documentation if you want to pursue possible reimbursement through your plan.
HSA or FSA funds may be used when permitted by your plan. Third-party financing through CareCredit and AdvanceCare may also be available, with eligibility and terms determined by the lender.
Review additional details on our pricing and insurance page.
Ketamine Therapy at Our Littleton Clinic
Our Littleton clinic serves patients from Littleton and the south Denver Metro area, including Highlands Ranch, Centennial, Englewood, and South Denver.
Vitalitas Westminster
26 West Dry Creek Circle, Suite 200, Littleton, CO 80120
Clinic hours:
Tuesday: 12 p.m. to 8 p.m.
Wednesday: 9 a.m. to 4 p.m.
Saturday: 10 a.m. to 3 p.m.
Phone:720-724-8075
Learn more about our Littleton clinic and locations.
If you are considering IV ketamine for persistent mental health symptoms or complex chronic pain, a consultation can help you understand how treatment works, what screening involves, and whether this approach may fit your care needs.
Frequently Asked Questions About Ketamine Therapy in Littleton
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Mental health infusions at Vitalitas are typically about 40 minutes. Chronic pain treatments are longer and more individualized. Your treatment length depends on the reason for treatment, your clinical plan, response, tolerance, and safety needs.
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For mental health treatment, a common starting course at Vitalitas is six infusions over approximately three to four weeks. Continued or maintenance treatment is individualized based on your response and clinical needs.
Chronic pain treatment schedules vary and are determined individually.
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Yes. You will need transportation home after an infusion. You should not drive, operate heavy machinery, drink alcohol, perform intense work, or make major decisions for the remainder of the treatment day.
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Most insurance plans do not cover IV ketamine therapy, and Vitalitas does not bill insurance directly. We can provide documentation if you choose to pursue possible reimbursement through your plan.
Request a Ketamine Therapy Consultation in Littleton
If previous mental health or chronic pain treatment has not provided enough relief, we can help you understand whether physician-led IV ketamine therapy may be worth considering.
Our process begins with careful screening, clear information, and an individualized clinical recommendation.
Medical Disclaimer
This page is for general educational purposes and is not a substitute for medical advice, diagnosis, or individualized treatment. Ketamine is FDA-approved as a general anesthetic. Its psychiatric and chronic pain uses are off-label. Treatment decisions should be made with a qualified healthcare professional after an appropriate evaluation.
Scientific Resources
Understanding Current Use of Ketamine for Emerging Areas of Therapeutic Interest, U.S. Food and Drug Administration, 2024.
A Consensus Statement on the Use of Ketamine in the Treatment of Mood Disorders, JAMA Psychiatry, 2017.
Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Chronic Pain, Regional Anesthesia and Pain Medicine, 2018.

