Pain Management in Littleton, CO
Explore physician-led IV ketamine therapy for selected chronic and neuropathic pain conditions at our Littleton clinic, serving Highlands Ranch, Centennial, Englewood, and South Denver.
Physician-Led Chronic Pain Care Serving Littleton and South Denver
At Vitalitas, our pain management services focus on medically supervised IV ketamine therapy for selected patients with persistent or complex pain that remains difficult to manage despite previous treatment. At our Littleton clinic at 26 West Dry Creek Circle, Suite 200, Littleton, CO 80120, we begin with a careful review of your symptoms, pain history, medications, previous care, health history, safety factors, and treatment goals.
Chronic pain is not one condition, and IV ketamine is not appropriate for every type of pain or every patient. We make individualized candidacy decisions based on the nature of your symptoms, what you have already tried, your broader medical picture, and whether outpatient ketamine treatment can be provided safely.
Chronic Pain Conditions We Evaluate in Littleton
Vitalitas evaluates selected patients for IV ketamine therapy across several confirmed chronic pain pathways:
Complex regional pain syndrome (CRPS/RSD): Ketamine may be considered for selected patients with persistent CRPS pain that remains difficult to manage despite previous care.
Neuropathic pain and neuropathy: Patients with burning, shooting, tingling, electric, or unusually sensitive nerve pain may be evaluated for off-label IV ketamine therapy.
Chronic migraine and refractory headaches: IV ketamine may be considered for selected patients with recurring migraine or headache symptoms that remain difficult to manage after previous treatment.
Other complex or persistent chronic pain: Some patients with difficult-to-manage chronic pain may be considered for treatment when clinically appropriate after individualized evaluation.
A diagnosis alone does not determine whether ketamine will be recommended. Pain pattern, duration, previous treatment, medications, medical history, clinical stability, and safety all influence candidacy.
Learn more about our broader approach to ketamine therapy for chronic pain.
How IV Ketamine Fits Into Chronic Pain Management
Ketamine is FDA-approved as a general anesthetic. Its use for chronic pain, neuropathic pain, CRPS, migraine, and other pain conditions is off-label, meaning ketamine has not been FDA-approved specifically to treat these conditions. The FDA provides additional context on the current use of ketamine in emerging areas of therapeutic interest.
Ketamine blocks NMDA receptors and affects glutamate signaling involved in pain processing. IV ketamine has been studied for several chronic pain conditions, although the strength of evidence and treatment approaches vary by diagnosis.
We approach treatment accordingly. Ketamine is not a cure for chronic pain, and it does not replace appropriate rehabilitation, primary care, pain-specialty treatment, or other care when those approaches remain important to your treatment plan.
How We Evaluate Chronic Pain Ketamine Candidacy
Our consultation process focuses on understanding the pain you are experiencing and whether outpatient IV ketamine may be a reasonable option within your broader treatment plan.
Before recommending treatment, we consider:
The type and location of your pain
How long symptoms have been present
Pain intensity, sensitivity, and flare patterns
How pain affects sleep, movement, work, and daily function
Medical history and current medications
Previous pain treatments and response
Relevant clinical and safety factors
Treatment goals and expectations
Whether outpatient ketamine treatment can be provided safely
If treatment appears appropriate, we create an individualized plan based on your clinical needs rather than applying the same protocol to every chronic pain patient.
When appropriate, we may also coordinate with your pain specialist, primary care clinician, or another provider involved in your ongoing care.
What to Expect From IV Ketamine Treatment for Chronic Pain
Chronic pain treatment at Vitalitas is more individualized than our mental health infusion pathway. Pain infusions are longer, and treatment length and frequency depend on your condition, symptoms, clinical plan, response, tolerance, and safety needs.
During an infusion, we monitor:
Heart rate
Heart rhythm
Blood pressure
Oxygen level
How you are feeling throughout treatment
Treatment takes place with physician oversight in a private room.
You will need transportation home afterward. For the remainder of the treatment day, you should avoid driving, operating heavy machinery, alcohol, intense work, and major decisions.
Follow-up is part of the care process. We review whether treatment is producing a meaningful change, how you are tolerating it, and whether continued IV ketamine remains clinically appropriate.
Physician-Led Chronic Pain Treatment in Littleton
Vitalitas’s physicians have anesthesiology backgrounds, and our chronic pain care emphasizes medical screening, individualized treatment decisions, monitoring, and realistic expectations.
Our approach includes:
Review of pain history and previous treatment
Medical and medication screening
Individualized candidacy decisions
Physician involvement throughout treatment
Clinical monitoring during infusions
Follow-up and reassessment
Coordination with established clinicians when appropriate
Persistent pain can affect more than pain intensity alone. Sleep, movement, sensitivity, physical function, flare patterns, and the ability to participate in everyday activities may all be relevant when we review your response to treatment.
We do not assume that every patient with chronic pain should receive ketamine or that every patient who begins treatment should continue indefinitely.
Pain Management at Our Littleton Clinic
Our Littleton clinic serves patients from Littleton and the south Denver Metro area, including Highlands Ranch, Centennial, Englewood, and South Denver.
Vitalitas Littleton
26 West Dry Creek Circle, Suite 200, Littleton, CO 80120
Phone:720-724-8075
A physician anesthesiologist is present during every infusion. Treatment takes place in a private room with clinical monitoring, and continued-treatment decisions are based on your response, tolerance, safety, and clinical needs.
Learn more about ourLittleton clinic and locations.
Frequently Asked Questions About Pain Management in Littleton
-
Vitalitas provides physician-led IV ketamine therapy for selected patients with CRPS/RSD, neuropathic pain and neuropathy, chronic migraine and refractory headaches, and other complex or persistent chronic pain when clinically appropriate.
All chronic pain uses of ketamine are off-label.
-
No. Ketamine is FDA-approved as a general anesthetic. Its use for chronic pain conditions is off-label. We explain this distinction as part of the evaluation process so you can consider treatment with clear expectations.
-
Ketamine may be considered for selected patients whose pain remains difficult to manage despite previous care. Candidacy depends on the type of pain you experience, your treatment history, medications, medical history, clinical stability, safety factors, goals, and whether outpatient ketamine treatment is appropriate.
-
Chronic pain infusions at Vitalitas are longer and more individualized than mental health infusions. Treatment length depends on your condition, clinical plan, response, tolerance, and safety needs.
-
Chronic pain treatment schedules are individualized. The number and frequency of infusions depend on your condition, response, tolerance, safety, and whether continued treatment remains clinically appropriate.
-
Ketamine should not be considered a replacement for other appropriate chronic pain care. Depending on your needs, your broader treatment may involve a pain specialist, primary care clinician, rehabilitation, medications, or other approaches. When appropriate, we coordinate with clinicians already involved in your care.
Request a Pain Management Consultation in Littleton
If persistent pain continues to affect your sleep, movement, work, or everyday activities despite previous care, we can help you understand what physician-led IV ketamine therapy involves and whether it may fit into your treatment plan.
Our process begins with careful evaluation, clear information, and an individualized clinical recommendation.
Medical Disclaimer
This page is for general educational purposes and is not a substitute for medical advice, diagnosis, or individualized treatment. Ketamine is FDA-approved as a general anesthetic. Its chronic pain uses are off-label. Treatment decisions should be made with a qualified healthcare professional after an appropriate evaluation.
Scientific Resources
Understanding Current Use of Ketamine for Emerging Areas of Therapeutic Interest, U.S. Food and Drug Administration, 2024.
Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Chronic Pain, Regional Anesthesia and Pain Medicine, 2018.

