Mental Health Services in Littleton, CO
Explore physician-led IV ketamine therapy for selected mental health conditions at our Littleton clinic, serving Highlands Ranch, Centennial, Englewood, and South Denver.
Physician-Led Mental Health Ketamine Care in Littleton
At Vitalitas, our mental health services focus on medically supervised IV ketamine therapy for selected patients whose symptoms remain difficult to manage despite previous treatment. At our Littleton clinic at 26 West Dry Creek Circle, Suite 200, Littleton, CO 80120, we begin with a clinical evaluation that considers your symptoms, mental health and medical history, medications, previous care, safety factors, and treatment goals.
Ketamine is not appropriate for every person or every mental health condition. We make individualized candidacy decisions, explain the role and limitations of treatment clearly, and consider ketamine within the context of your broader mental health care rather than as a replacement for it.
Mental Health Conditions We Evaluate in Littleton
Vitalitas evaluates selected patients for IV ketamine therapy across several confirmed mental health pathways:
Treatment-resistant depression: IV ketamine may be considered when depression has not improved enough with previous treatment.
Post-traumatic stress disorder (PTSD): Selected patients whose PTSD symptoms remain difficult to manage despite previous care may be evaluated for treatment.
Anxiety and panic disorders: IV ketamine may be considered for selected patients with persistent anxiety or panic symptoms after previous treatment.
Obsessive-compulsive disorder (OCD): Selected patients with OCD may be evaluated for IV ketamine when symptoms remain difficult to manage despite established care.
A diagnosis alone does not mean ketamine will be recommended. Your symptoms, treatment history, medications, clinical stability, safety factors, and overall care needs all influence candidacy.
Learn more about our broader mental health ketamine care.
How IV Ketamine Fits Into Mental Health Care
Ketamine is FDA-approved as a general anesthetic. Its use for depression, PTSD, anxiety, OCD, and other psychiatric conditions is off-label, meaning ketamine has not been FDA-approved specifically to treat these mental health conditions. The FDA provides additional context on the current use of ketamine in emerging areas of therapeutic interest.
Ketamine affects glutamate signaling through NMDA receptors. Research into psychiatric uses varies by condition, with the strongest body of evidence focused on depression and treatment-resistant depression. We do not present ketamine as a guaranteed solution or as a replacement for psychotherapy, psychiatric care, medication management, or other established treatment when those approaches remain appropriate.
How We Evaluate Mental Health Ketamine Candidacy
Our consultation process is designed to determine whether outpatient IV ketamine therapy makes clinical sense for your individual situation.
Before recommending treatment, we consider:
Your current symptoms and their impact on daily life
Mental health and medical history
Current medications
Previous psychotherapy, medication, and other treatment
Treatment response and remaining symptoms
Clinical stability and relevant safety factors
Treatment goals and expectations
Whether outpatient ketamine treatment can be provided safely
If IV ketamine appears appropriate, we develop an individualized treatment plan. If it does not appear to be a good clinical fit, we believe explaining that clearly is part of responsible care.
When appropriate, we may also coordinate with the psychiatrist, therapist, primary care clinician, or other provider involved in your existing mental health treatment.
Conditions We Treat
At Vitalitas Denver, we provide physician-led IV ketamine therapy for selected patients experiencing difficult-to-manage mental health and chronic pain conditions. Explore our individualized, off-label treatment options when previous care has not provided sufficient relief for your symptoms.
Anxiety
Explore whether IV ketamine therapy may be an option when persistent worry, fear, and unease have not responded to previous care.
Migraine
Discover if IV ketamine therapy may be an appropriate next step when difficult-to-control migraine attacks persistently disrupt your daily life.
CRPS
Consider physician-led IV ketamine therapy when persistent pain, sensitivity, swelling, or physical limitations continue despite previous pain management treatments.
Neuropathy
Explore an alternative approach for neuropathic pain when burning, tingling, shooting, or hypersensitive nerve pain remains difficult to manage with previous care.
OCD
Consider this off-label option when intrusive thoughts, repetitive compulsions, checking behaviors, or reassurance-seeking persistently interfere with your daily life.
Depression
Get support for depression when persistent sadness, low energy, and loss of interest continue to affect your everyday routines despite prior treatment.
PTSD
Find individualized support when intrusive memories, avoidance, hypervigilance, or severe sleep disruption continue despite established trauma-focused mental health care.
What to Expect From Mental Health Ketamine Treatment
If treatment moves forward, IV ketamine is administered with physician oversight and clinical monitoring.
During an infusion, we monitor:
Heart rate
Heart rhythm
Blood pressure
Oxygen level
How you are feeling throughout treatment
Mental health infusions at Vitalitas are typically about 40 minutes. A common starting course is six infusions over approximately three to four weeks. After that initial course, we review your response before making individualized decisions about continued or maintenance treatment.
The number of treatments you ultimately receive depends on your clinical needs, response, tolerance, safety, and whether continued treatment remains appropriate.
After an infusion, you will need transportation home. For the remainder of the treatment day, you should avoid driving, operating heavy machinery, alcohol, intense work, and major decisions.
Physician Oversight and Mental Health Care Coordination
Vitalitas is a physician-led practice with an anesthesiology foundation. Medical screening, monitoring, and individualized treatment decisions are central to how we provide ketamine therapy.
Our approach includes:
Individualized candidacy decisions
Review of health history and medications
Physician involvement throughout treatment
Clinical monitoring during infusions
Attention to response and tolerability
Follow-up before ongoing treatment decisions
Coordination with outside clinicians when appropriate
Ketamine can cause short-term physical and perceptual effects, which is one reason careful screening and medical monitoring matter.
Ketamine is also only one possible part of a broader mental health treatment plan. Depending on your needs, your ongoing care may include psychotherapy, psychiatric treatment, medication management, primary care, or other support. When appropriate, we coordinate with the clinicians already involved in your care.
Mental Health Services at Our Littleton Clinic
Our Littleton clinic provides physician-led IV ketamine therapy for selected mental health patients from Littleton and the south Denver Metro area, including Highlands Ranch, Centennial, Englewood, and South Denver.
Vitalitas Littleton
26 West Dry Creek Circle, Suite 200, Littleton, CO 80120
Phone: 720-724-8075
A physician anesthesiologist is present during every infusion. Treatment takes place in a private room with clinical monitoring, and follow-up is used to review response, tolerability, and whether continued treatment remains appropriate.
Learn more about our Littleton clinic and locations.
Frequently Asked Questions About Mental Health Services in Littleton
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Vitalitas provides physician-led IV ketamine therapy for selected patients with treatment-resistant depression, PTSD, anxiety and panic disorders, and OCD. Ketamine use for these psychiatric conditions is off-label.
Treatment begins with an evaluation to determine whether outpatient IV ketamine therapy is appropriate for your individual needs.
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No. Ketamine is FDA-approved as a general anesthetic. Its use for depression, PTSD, anxiety, OCD, and other psychiatric conditions is off-label. We discuss that distinction as part of the evaluation process so you can consider treatment with clear expectations.
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Ketamine may be considered for selected patients whose symptoms remain difficult to manage despite previous treatment. Candidacy depends on your diagnosis, symptoms, treatment history, medications, medical and mental health history, clinical stability, safety factors, and whether outpatient ketamine treatment is appropriate.
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Mental health infusions at Vitalitas are typically about 40 minutes. Your overall care plan is individualized according to your response, tolerance, clinical needs, and safety.
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A common starting mental health course at Vitalitas is six infusions over approximately three to four weeks. We then review your response before making individualized decisions about continued or maintenance treatment.
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Ketamine should not be considered a replacement for psychotherapy, psychiatric care, medication management, or other established mental health treatment when those approaches remain appropriate. When useful, we may coordinate with the clinicians already involved in your care.
Request a Mental Health Ketamine Consultation in Westminster
If depression, PTSD, anxiety, OCD, or related symptoms remain difficult to manage despite previous care, we can help you understand what physician-led IV ketamine therapy involves and whether it may fit into your treatment plan.
Our process begins with careful evaluation, clear information, and an individualized clinical recommendation.
Medical Disclaimer
This page is for general educational purposes and is not a substitute for medical advice, diagnosis, or individualized treatment. Ketamine is FDA-approved as a general anesthetic. Its psychiatric uses are off-label. Treatment decisions should be made with a qualified healthcare professional after an appropriate evaluation.
Scientific Resources
Understanding Current Use of Ketamine for Emerging Areas of Therapeutic Interest, U.S. Food and Drug Administration, 2024.
A Consensus Statement on the Use of Ketamine in the Treatment of Mood Disorders, JAMA Psychiatry, 2017.

